ETOSEC-MR Tablets
Etoricoxib 60mg with Thiocolchicoside 4mg Tablets
Reference MRP
₹280.00
Standard Packaging
10 Strips x 27 Film-Coated Tablets per carton (270 Tablets Box)
ETOSEC-MR Tablets deliver targeted anti-inflammatory and muscle relaxant therapy in a single formulation. Manufactured under WHO-GMP Schedule M standards by Redition Pharma, this combination pairs Etoricoxib — a highly selective cyclooxygenase-2 (COX-2) inhibitor with superior GI tolerability — with Thiocolchicoside, a centrally-acting GABA-ergic and glycinergic muscle relaxant that reduces pathological muscle spasm without sedation. Ideal for acute musculoskeletal conditions where both inflammation and muscle spasm contribute to pain.
Lic. 12116801000249Request batch Certificate of Analysis (COA), technical dossier, and institutional rate contracts.
Pharmacological Advantages & Clinical Evidence
- 01
Selective COX-2 Inhibition (Etoricoxib 60mg): Potent anti-inflammatory and analgesic action with minimal gastric mucosal irritation compared to non-selective NSAIDs.
- 02
Centrally-Acting Muscle Relaxant (Thiocolchicoside 4mg): GABA-A and glycine receptor agonist providing rapid skeletal muscle relaxation without CNS sedation.
- 03
Dual-Target Mechanism: Simultaneously addresses inflammatory pain cascades and reflex muscle spasm for comprehensive musculoskeletal relief.
- 04
Convenient Once/Twice Daily Dosing: Etoricoxib's long 22-hour half-life enables sustained therapeutic coverage with fewer daily doses.
- 05
Authentic Batch Verification: Batch No. RTG225139, Mfg. Lic. No. 1538-B & 1538-OSP with complete regulatory Certificate of Analysis (COA) compliance.
- 06
10 x 27 Tablets Packaging: Alu-Alu moisture-barrier blister foils inside UV-resistant clinical mono-carton for institutional supply.
Clinical Indications
- —Acute & Chronic Low Back Pain with Muscle Spasm
- —Cervical Spondylosis & Cervicobrachial Syndrome
- —Osteoarthritis (OA) with Associated Muscle Rigidity
- —Rheumatoid Arthritis Flares with Periarticular Spasm
- —Post-Operative Orthopedic Pain & Rehabilitation
- —Ankylosing Spondylitis with Paraspinal Muscle Spasm
Technical Specifications
- Active Ingredient
- Etoricoxib, Thiocolchicoside
- Dosage Form
- Film-Coated Tablet
- Pharmacopoeial Standard
- IP / In-House Validated Monograph
- Formulation Category
- Selective COX-2 Inhibitor & GABA-ergic Muscle Relaxant
- Administration
- As directed by the physician (Schedule H Prescription). Typically 1 tablet once or twice daily after food with water. Maximum duration as per physician guidance.
- Packaging Format
- 10 Strips x 27 Film-Coated Tablets per carton (270 Tablets Box)
- Storage & Stability
- Store below 25°C in a dry place. Protect from direct sunlight and moisture. Keep out of reach of children. | Shelf life: 24 Months from manufacturing date
Mechanism of Action
Etoricoxib selectively inhibits cyclooxygenase-2 (COX-2) at the site of inflammation, blocking prostaglandin E2 synthesis and reducing pain, swelling, and inflammatory hyperalgesia without significantly inhibiting COX-1-mediated gastric mucosal protection. Thiocolchicoside acts centrally as an agonist at GABA-A and glycine receptors in the spinal cord and supraspinal centers, reducing pathological muscle tone and spasm through inhibition of polysynaptic reflex arcs.
Institutional FAQs
What is ETOSEC-MR Tablets used for?
ETOSEC-MR is prescribed for musculoskeletal conditions involving both inflammation and muscle spasm, such as acute low back pain, cervical spondylosis, osteoarthritis with muscle rigidity, and post-operative orthopedic pain.
Is ETOSEC-MR safer on the stomach than traditional NSAIDs?
Yes. Etoricoxib is a selective COX-2 inhibitor, meaning it provides anti-inflammatory action while sparing COX-1, the enzyme responsible for protective gastric mucus production. This results in significantly lower GI side effects compared to non-selective NSAIDs like diclofenac or ibuprofen.
Does Thiocolchicoside cause drowsiness?
Unlike many muscle relaxants, Thiocolchicoside acts through GABA-ergic and glycinergic pathways without significant CNS sedation, making ETOSEC-MR suitable for patients who need to remain alert during daily activities.
Procurement & Dossier Request for ETOSEC-MR Tablets
Submit your hospital tender requirements, rate-contract bids, or Certificate of Analysis (COA) requests. Our regulatory trade desk dispatches validated batch documentation within 24 hours.
Founder & Managing Director
Nilesh Kumar
Direct Sales & Dispatch Line
+91 79877 79819Regulatory Dossiers & RFQ
reditionpharma@gmail.comRegistered Corporate Office
101, 1st Floor, Bhumi Park Society, Punagam Chorasi Bombay Market, Surat, Gujarat 395010, India